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alpha cop  (Atlas Antibodies)


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    Atlas Antibodies alpha cop
    Alpha Cop, supplied by Atlas Antibodies, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/alpha cop/product/Atlas Antibodies
    Average 92 stars, based on 1 article reviews
    alpha cop - by Bioz Stars, 2026-02
    92/100 stars

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    COPI vesicles are decreased in osteoporosis. ( A , B ) Representative micro-CT images ( A ) and quantitative analysis of bone mass and bone microarchitecture parameters ( B ) in tibia from CON (control) and OP (osteoporosis) rats. Scale bar: 1 mm. n = 3 per group. BV/TV, bone volume/tissue volume; Tb. Th, trabecular thickness; Tb. N, trabecular number; Tb. Sp, trabecular separation. Scale bar: 2 mm. ( C , D ) H&E staining ( C ) and Masson staining ( D ) of tibia from the CON and OP rats. Scale bar: 500 μm. Arrows: bone trabecula. ( E , F ) Representative immunohistochemical images of proximal tibia sections’ staining with COPI proteins <t>(α-COP</t> and β-COP) and quantitative analysis. Scale bar: 20 μm. n = 3 per group. Arrows: osteoblasts. Data are means ± SD, and p values were quantified using t test. * p < 0.05; ** p < 0.01, *** p < 0.001.
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    COPI vesicles are decreased in osteoporosis. ( A , B ) Representative micro-CT images ( A ) and quantitative analysis of bone mass and bone microarchitecture parameters ( B ) in tibia from CON (control) and OP (osteoporosis) rats. Scale bar: 1 mm. n = 3 per group. BV/TV, bone volume/tissue volume; Tb. Th, trabecular thickness; Tb. N, trabecular number; Tb. Sp, trabecular separation. Scale bar: 2 mm. ( C , D ) H&E staining ( C ) and Masson staining ( D ) of tibia from the CON and OP rats. Scale bar: 500 μm. Arrows: bone trabecula. ( E , F ) Representative immunohistochemical images of proximal tibia sections’ staining with COPI proteins <t>(α-COP</t> and β-COP) and quantitative analysis. Scale bar: 20 μm. n = 3 per group. Arrows: osteoblasts. Data are means ± SD, and p values were quantified using t test. * p < 0.05; ** p < 0.01, *** p < 0.001.
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    COPI vesicles are decreased in osteoporosis. ( A , B ) Representative micro-CT images ( A ) and quantitative analysis of bone mass and bone microarchitecture parameters ( B ) in tibia from CON (control) and OP (osteoporosis) rats. Scale bar: 1 mm. n = 3 per group. BV/TV, bone volume/tissue volume; Tb. Th, trabecular thickness; Tb. N, trabecular number; Tb. Sp, trabecular separation. Scale bar: 2 mm. ( C , D ) H&E staining ( C ) and Masson staining ( D ) of tibia from the CON and OP rats. Scale bar: 500 μm. Arrows: bone trabecula. ( E , F ) Representative immunohistochemical images of proximal tibia sections’ staining with COPI proteins <t>(α-COP</t> and β-COP) and quantitative analysis. Scale bar: 20 μm. n = 3 per group. Arrows: osteoblasts. Data are means ± SD, and p values were quantified using t test. * p < 0.05; ** p < 0.01, *** p < 0.001.
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    Image Search Results


    COPI vesicles are decreased in osteoporosis. ( A , B ) Representative micro-CT images ( A ) and quantitative analysis of bone mass and bone microarchitecture parameters ( B ) in tibia from CON (control) and OP (osteoporosis) rats. Scale bar: 1 mm. n = 3 per group. BV/TV, bone volume/tissue volume; Tb. Th, trabecular thickness; Tb. N, trabecular number; Tb. Sp, trabecular separation. Scale bar: 2 mm. ( C , D ) H&E staining ( C ) and Masson staining ( D ) of tibia from the CON and OP rats. Scale bar: 500 μm. Arrows: bone trabecula. ( E , F ) Representative immunohistochemical images of proximal tibia sections’ staining with COPI proteins (α-COP and β-COP) and quantitative analysis. Scale bar: 20 μm. n = 3 per group. Arrows: osteoblasts. Data are means ± SD, and p values were quantified using t test. * p < 0.05; ** p < 0.01, *** p < 0.001.

    Journal: International Journal of Molecular Sciences

    Article Title: COPI Vesicle Disruption Inhibits Mineralization via mTORC1-Mediated Autophagy

    doi: 10.3390/ijms25010339

    Figure Lengend Snippet: COPI vesicles are decreased in osteoporosis. ( A , B ) Representative micro-CT images ( A ) and quantitative analysis of bone mass and bone microarchitecture parameters ( B ) in tibia from CON (control) and OP (osteoporosis) rats. Scale bar: 1 mm. n = 3 per group. BV/TV, bone volume/tissue volume; Tb. Th, trabecular thickness; Tb. N, trabecular number; Tb. Sp, trabecular separation. Scale bar: 2 mm. ( C , D ) H&E staining ( C ) and Masson staining ( D ) of tibia from the CON and OP rats. Scale bar: 500 μm. Arrows: bone trabecula. ( E , F ) Representative immunohistochemical images of proximal tibia sections’ staining with COPI proteins (α-COP and β-COP) and quantitative analysis. Scale bar: 20 μm. n = 3 per group. Arrows: osteoblasts. Data are means ± SD, and p values were quantified using t test. * p < 0.05; ** p < 0.01, *** p < 0.001.

    Article Snippet: The primary antibodies LC3B (A19665, ABclonal, Wuhan, China), BECLIN1 (A21695, ABclonal, Wuhan, China), α-COP (A19651, ABclonal, Wuhan, China), and β-COP (ab2899, Abcam, Boston, MA, USA) were used.

    Techniques: Micro-CT, Control, Staining, Immunohistochemical staining

    BFA-induced COPI vesicle disruption inhibits osteogenic effect. ( A , B ) Representative immunofluorescence images staining for β-COP (red) and the quantitative analysis of β-COP expression in control (CON) or osteogenic differentiation medium (ODM) condition for 3 d. The nucleus was highlighted by DAPI. Scale bar: 5 μm. n = 5 per group. ( C , D ) Western blot of COPI proteins (α-COP and β-COP) and quantitative analysis. n = 3 per group. ( E , F ) Representative immunofluorescence images staining for β-COP (red) and the quantitative analysis of β-COP expression with or without Brefeldin A (BFA) in ODM condition for 3 d. The nucleus was highlighted by DAPI. Scale bar: 5 μm. n = 5 per group. ( G , H ) Western blot of COPI proteins (α-COP and β-COP) and quantitative analysis. n = 3 per group. ( I , J ) ALP staining ( I ) and the quantitative analysis ( J ). Scale bar: 150 μm. n = 3 per group. ( K , L ) Western blot of mineralization-related proteins and quantitative analysis. n = 3 per group. Data are means ± SD, and p values were quantified using t test. * p < 0.05; ** p < 0.01, *** p < 0.001.

    Journal: International Journal of Molecular Sciences

    Article Title: COPI Vesicle Disruption Inhibits Mineralization via mTORC1-Mediated Autophagy

    doi: 10.3390/ijms25010339

    Figure Lengend Snippet: BFA-induced COPI vesicle disruption inhibits osteogenic effect. ( A , B ) Representative immunofluorescence images staining for β-COP (red) and the quantitative analysis of β-COP expression in control (CON) or osteogenic differentiation medium (ODM) condition for 3 d. The nucleus was highlighted by DAPI. Scale bar: 5 μm. n = 5 per group. ( C , D ) Western blot of COPI proteins (α-COP and β-COP) and quantitative analysis. n = 3 per group. ( E , F ) Representative immunofluorescence images staining for β-COP (red) and the quantitative analysis of β-COP expression with or without Brefeldin A (BFA) in ODM condition for 3 d. The nucleus was highlighted by DAPI. Scale bar: 5 μm. n = 5 per group. ( G , H ) Western blot of COPI proteins (α-COP and β-COP) and quantitative analysis. n = 3 per group. ( I , J ) ALP staining ( I ) and the quantitative analysis ( J ). Scale bar: 150 μm. n = 3 per group. ( K , L ) Western blot of mineralization-related proteins and quantitative analysis. n = 3 per group. Data are means ± SD, and p values were quantified using t test. * p < 0.05; ** p < 0.01, *** p < 0.001.

    Article Snippet: The primary antibodies LC3B (A19665, ABclonal, Wuhan, China), BECLIN1 (A21695, ABclonal, Wuhan, China), α-COP (A19651, ABclonal, Wuhan, China), and β-COP (ab2899, Abcam, Boston, MA, USA) were used.

    Techniques: Disruption, Immunofluorescence, Staining, Expressing, Control, Western Blot

    Antibodies and inhibitors. WB, Western blot; IP, immunoprecipitation; IF, immunofluorescence; PLA, proximity ligation assay.

    Journal: Science Advances

    Article Title: HPV is a cargo for the COPI sorting complex during virus entry

    doi: 10.1126/sciadv.adc9830

    Figure Lengend Snippet: Antibodies and inhibitors. WB, Western blot; IP, immunoprecipitation; IF, immunofluorescence; PLA, proximity ligation assay.

    Article Snippet: α-COP , Rabbit , HPA028024; Millipore Sigma , WB.

    Techniques: Western Blot, Immunoprecipitation, Immunofluorescence, Ligation, Solvent, Concentration Assay